Hi @JColvin Thanks for your reply The voltage at different caps are as follows C291 - 12.08V C293 - 3.3V C271 - 5.02V C277 - 1.00V C302 - 0V C264 - 12V C303 - 0V C296 - 1.2V There is no visible physical damage to any ICs. None of the status LEDs are on. The peripherals attached to the system were Zmod ADC 1410 on ZMODA, and one serial LCD on the PMOD connected through flying wires. It looks like that IC29 has somehow locked every thing, but I can not find any datasheet of it. Thanks Saeed